It is a longstanding conjecture that every simple drawing of a complete graph
on

vertices contains a crossing-free Hamiltonian cycle. We
strengthen this conjecture to there exists a crossing-free
Hamiltonian path between each pair of vertices and show that this stronger
conjecture holds for several classes of simple drawings, including strongly
c-monotone drawings and cylindrical drawings. As a second main contribution,
we give an overview on different classes of simple drawings and investigate
inclusion relations between them up to weak isomorphism.